If you are using Microsoft Teams for all your work and communications requirements, you’ve probably become quite familiar with a range of different error messages and shortcomings within the service. Thankfully most of these can be resolved, including error 80080300 which prevents Teams from launching correctly or signing you in properly.

Related: How to create folders in the Start menu on Windows 11. Create, Rename, Remove.

Microsoft Teams is one of the most used programs on the market at the moment and is an important tool for connecting employees who work remotely with their colleagues. Everyone who has been using Microsoft Teams for some time will be familiar with Teams’ almost endless list of error messages and sign in problems. Although Teams can be accessed from the web, the application is the preferred method for most companies.

We’ve covered dozens of different Microsoft Teams errors over the last few years and have found that most of them are either launch or sign in related and primarily come from the Windows app. Which means that almost all issues are caused by some kind of corruption within Teams. Thankfully, this makes solving Teams' error 80080300 and those like it relatively straightforward, so follow along as we guide you through the process.

How do you fix Microsoft Teams error 80080300? Clear the Microsoft Teams Cache to solve error 80080300.

A quick and easy way to solve this problem is to clear your Microsoft Teams cache. On Windows 10 & 11 you’ll need to do the following.

  • First, open the Run tool by pressing Windows Key + R.
  • Next copy and paste %appdata%\Microsoft\teams\Cache into the text box and press Enter. This will open a File Explorer window in the exact location of one of Teams caches. Press Ctrl+A to select everything within the location then press Delete to delete it all. Once you have deleted everything do the same for all of the following locations:

%appdata%\Microsoft\teams\application cache\cache

%appdata%\Microsoft\teams\blob_storage

%appdata%\Microsoft\teams\databases.

%appdata%\Microsoft\teams\GPUcache

%appdata%\Microsoft\teams\IndexedDB

%appdata%\Microsoft\teams\Local Storage

%appdata%\Microsoft\teams\tmp

How to fix Microsoft Teams error 80080300

After you have cleared all of the above locations, restart your computer and check to see if the problem has been solved.

Uninstall and reinstall Microsoft Teams to fix 80080300.

If clearing the Microsoft Teams cache didn’t solve this issue, you’ll need to combine it with a clean installation of Microsoft Teams.

  • So make sure you have cleared your Microsoft Teams cache, then uninstall Microsoft Teams on your device.
  • After you have uninstalled Microsoft Teams, Restart your computer, then download the latest version of Microsoft Teams for your device.

If this doesn’t solve your problem and you are desperate to get into Microsoft Teams just use the web version for the time being. You may have to wait for a Windows update to solve the problem with Microsoft Teams.

Can’t sign into Microsoft Teams using the web version?

If you can’t sign into Microsoft Teams using the web version because you keep getting stuck in a weird email address loop. Check out the following guide: How to fix Microsoft Teams can’t change sign-in email address.